La carnosidad o pterigión es un crecimiento carnoso, en forma de cuña, en la córnea del ojo. Este crecimiento ¿Cuál es el tratamiento para la carnosidad?. 1 Mar Recent Posts. Test. Recent Comments. Archives. January Categories. Uncategorized. Meta. Log in · Entries RSS · Comments RSS. La carnosidad (pterigion) es un crecimiento de un tejido el cual invade la cornea (la ventana transparante del ojo). Es un proceso anormal la cual conjuntiva (es.

Author: Gomi Shara
Country: Pakistan
Language: English (Spanish)
Genre: Science
Published (Last): 19 February 2011
Pages: 480
PDF File Size: 18.38 Mb
ePub File Size: 1.8 Mb
ISBN: 707-5-53166-425-2
Downloads: 66326
Price: Free* [*Free Regsitration Required]
Uploader: Samucage

P53 expresion in tratamiengo limbal basal cells in pingueculae, pterygia and limbal tumors. Imnunohistochemical study of p53, pterigion tratamiento and PCNA in pterygium. C The inflammatory reaction increases and begins to take the pterigion tratamiento aspect that will turn into pterygium.

D Detail of lesion in the limbus area.

This procedure is effective in a high degree of cases but there are still a high pterigion tratamiento of relapses that require further surgery. It is thought that the main trigger factor is the ultraviolet-light pterigion tratamiento, therefore the incidence is much higher in equatorial countries, with high rates of insolation Invest Ophthalmol Vis Sci The UV light act on the LESC causing mutation in the gene responsible for the p53 protein synthesis, the gene loses its ability to act as a transcription factor, resulting in uncontrolled cell proliferation and a change to the signals that activate growth factors and the cyclins D1-Cdk4 11, Hence, we shall stress to the patients to avoid this type of radiation, either by reducing their exposure to sunlight or using good quality wrap-around sunglasses that have the right UV filter.

Pterigion tratamiento the removal, if it is of small size, the procedure is concluded after suturing the edges of the healthy conjunctiva. Perhaps today the most recommended step in preventing pterigion tratamiento or when it has hardly started would be the VEGF inhivitors infiltration in the danger zone Other drugs, pterigion tratamiento as Thiotepa or 5-Fluorouracil 20 have not proven the same level of effectiveness.


Menú principal

The standard treatment is surgery: It has even been proposed the instillation of Mitomycin C as eye drops in complex pterigion tratamiento, where recurrence would likely happen. Potential role of angiogenesis. A dose response curve Am J Ophthalmol In recent years, we observed an increase in the incidence of pterygium, both primary and recurrent.

Histochemical studies and molecular biology show that in the pterygium, trwtamiento LESC Limbal Epithelial Stem Tratamiiento express a mutated tumour suppressor gene that causes the presence of protein p53 11,12a pterigion tratamiento tratzmiento in various human cancers and in lesions of actinic skin 13which suggests that pterygium would be a proliferative disorder similar to a tumour.

C Pterygium growing onto the cornea. First, it is obvious that we must protect the eyes from the UV pterigion tratamiento.


The origin of this tissue proliferation is derived from the basal epithelial stem cells of the limbal bed LESCthat are activated and pterigion tratamiento into conjunctival pterigion tratamiento 2. A Corneal invasion pterigion tratamiento. It is unclear the cause of relapses but everything suggests that there is still some degree of inflammatory reaction and a limbus condition that facilitates the new fibrovascular proliferation and corneal invasion, pterigion tratamiento well as the persistence of the casual factor, the UV radiation; for it is necessary to take these three factors much into account.

Their identification opens a new pathway to treatment of pterygium. The frecuency distribution of ocular disease by age in Imo Satate Nigeria. Arch Ophthalmol In the postoperative period, it is also necessary to control inflammation, especially in the early stages, thus it is indispensable to administer topical steroids. rtatamiento

The implications of the p53 gene pterigion tratamiento is that LESC grow uncontrolled 14migrate and grow onto the cornea through the basal pterigion tratamiento 15pterigion tratamiento along conjunctival pterigiion and inducing the formation of fibrovascular tissue at this level, due to increased levels of inflammatory mediators, proliferative and angiogenic factors, such as found in the histopathologic and histochemical analysis As for the second factor, the inflammatory reaction, it is necessary to take pre-operative, intraoperative and postoperative measures.


At an pteriggion level, it is advisable to apply drugs that inhibit fibroblast proliferation, such as Mitomycin C.

Another option is the implantation of ex vivo culture stem cells on amniotic pterigion tratamiento support Consequently, fibrovascular proliferation, remodelling of connective tissue, angiogenesis and corneal invasion occur. The first UV light effect on the tissues pterigion tratamiento an elastic degeneration of the own subconjunctival substance.

J Am OptomAssoc Sun exposure and Pterygium of the eye. In summary, UV radiation and micro trauma lead to a chronic pterigion tratamiento process, with function loss of the natural barrier of the corneal conjunctival limbus.

PTERYGIUM: What is it? How is it treated? | Pterigion

pterigion tratamiento This is a crucial data when treating pterygium surgically: Pterigion tratamiento possible, it is also better to use a conjunctival graft pterigoon the same eye, taken from the superior bulbar conjunctiva.

Elastic fibber components and protease inhibitors in pinguecula. The surgical technique must be careful, by shearing off all the triangular-shaped pterygium head and body. B The size of the lesion and vascularization increases.

¿Qué es el pterigión?

The graft may be sutured or fixed through adherent substances pterigion tratamiento as fibrin Tissucol TM. If possible, non-inflammatory sutures must be used, like nylon, since vicryl being of resorbable type more commonly used might encourage fibrovascular re-growth.

Curr Eye Res pterigion tratamiento, Anmiotic membrane transplantation after extensive removal of primary and recurrent trayamiento. How is it treated?

A Small yellowish lesion surrounded by prominent vessels. It is essential that the corneal and limbic surface be regular and pterigion tratamiento, otherwise the fibrovascular pteriyion of the conjunctiva will grow back, starting the risk of pterigion tratamiento.